Saint Matrona worked many miracles both during her life and after her death, and was revered throughout Chios for her virtuous life and holiness. She showed charity to the poor, and was able to heal the sick.
The service to Saint Matrona was composed by Metropolitan Niketas of Rhodes. It was found in a codex from 1455, which would indicate that she died sometime before this date.
Saint Matrona is also commemorated on July 15 (the finding of her head).