He once met a friend who gazed into his face for a long time with astonishment. When Niphon asked why he was staring, the friend replied, “I have never seen your face like this before. It is black, like that of an Ethiopian.” These words showed to Niphon his fallen state, and he began to cry out to the Mother of God, begging Her intercession.
After an intense and long prayer he saw that the face of the Mother of God on the holy icon was radiantly bright with a smile. From that time Niphon prayed incessantly to the Queen of Heaven. If he fell into sin, the face of the Mother of God turned away from him, but after tears and prayers, She mercifully turned toward him again.
Finally, Niphon completely turned his life around and began to spend his time in prayer and repentance. After an illness, from which he received healing from the Mother of God, he received the Holy Mysteries, and then accepted monastic tonsure and intensified his efforts, exhausting his body in the struggle against the passions.
This struggle lasted for many years, and devils often attacked Saint Niphon, but with the help of God he overcame them. He received from God the gift to discern evil spirits and defeat them, and also to see the departure of the soul after death. Already advanced in age, and arriving at Alexandria, he was pointed out to the Patriarch in a vision as one worthy to assume the office of bishop. They made him bishop of the city of Constantia on the island of Cyprus. However, he did not remain there for long. Saint Niphon knew the time of his death three days beforehand. Saint Athanasius the Great visited him before his blessed repose. On his deathbed the saint was granted to see angels and the All-Pure Mother of God.