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In search of solitude, the monk went to the Mulyanka River and settled at the place where the city Perm is now. Here he converted to Christianity the pagan Ostyaks and Voguli. Then Saint Tryphon withdrew to the River Chusova and founded a monastery in honor of the Dormition of the Most Holy Theotokos.
In 1580 he arrived in the city of Khynov in Vyatsk diocese, and he also founded a monastery there in honor of the Dormition and was made Archimandrite. Being a strict ascetic, he wore a hairshirt on his body and also heavy chains. The soul of the Elder longed to enlighten the lost with the light of faith in Christ. He devoted all his energy to this holy effort.
Before his death, Saint Tryphon wrote a last testament to the brethren, in which he says, “Fathers and brethren, the flock gathered about Christ! Heed me, a sinner. Though I am coarse and worse than any, God and His All-Pure Mother have permitted me, a sinner, to manage His household. I beseech you, for the sake of the Lord and His Mother, to have spiritual love among yourselves. Without this no virtue is complete before God. The lips of Christ spoke to the disciples, “Love one another” (John. 13:34). And in the words of the Apostle Paul, “Bear one another’s burdens” (Gal. 6: 2). Do not condemn one another before God, whether in the temple or in the cell, either alone or in common with the brethren. Pray with the fear of God. And by no means neglect church singing; although there are other matters, hasten to church to God for spiritual song. First give to God what is God’s, and then fulfill the other matters.” Saint Tryphon fell asleep in the Lord in old age in 1612. He was buried in the Vyatka monastery he founded.