
In the city of Edessa at this time lived the soldier John, a pious Christian. When the persecution started, he went to Jerusalem and there he heard about Saint Cyrus. He began to search for him, going first to Alexandria and then to Arabia. When Saint John finally found Saint Cyrus, he remained with him and became his faithful follower.
They learned of the arrest of the Christian woman Athanasia and her three young daughters. Theoctiste was fifteen; Theodota, was thirteen; and Eudoxia, was eleven. Saints Cyrus and John hastened to the prison to help them. They were concerned that faced with torture, the women might renounce Christ.

At the same place they executed the Holy Unmercenaries Cyrus and John. Christians buried their bodies in the church of the holy Evangelist Mark. In the fifth century the relics of Saints Cyrus and John were transferred from Canopis to Manuphin. Later on their relics were transferred to Rome, and from there to Munchen (Munich) (another account is located under June 28).
Saints Cyrus and John are invoked by those who have difficulty in sleeping.
Troparion — Tone 5
You have given us the miracles of Your martyrs, Cyrus and John, / as an invincible rampart; / through their prayers, frustrate the plans of the heathens, / and strengthen the faith of the Orthodox Christians, / for You alone are good and love mankind.
Kontakion — Tone 3
Podoben: “Today the Virgin...” / Having received the gift of miracles through divine grace, O saints, / you work wonders in the world unceasingly. / You remove all of our passions through your invisible surgery, / divinely-wise Cyrus and glorious John, / for you are truly divine physicians.